Technology and method for inclusion of colloid mill grinding device in β -cyclodextrin colloid mill Except for the motor and some parts, all the parts in contact with the materials are made of high-strength stainless steel 304, 316, 316L, 2205 and alloy steel. Especially, the key dynamic and static grinding discs are strengthened. Therefore, they have good corrosion resistance and wear resistance, which makes the processed materials pollution-free, hygienic and pure, and can also be customized according to the special requirements of users. To optimize the extraction process and method of volatile oil from Schizonepeta tenuifolia and the inclusion of β -cyclodextrin colloid mill. The extraction process of volatile oil from Schizonepeta tenuifolia was studied by water distillation, with the amount of soaking water and distillation time as the investigation factors and the volume of volatile oil as the evaluation index. Taking the ratio of β -cyclodextrin to volatile oil, the amount of water and grinding time as the investigation factors, and the inclusion rate of volatile oil as the evaluation index, the inclusion process was optimized by colloid mill grinding method and orthogonal test, and the inclusion compound was verified by ultraviolet spectrophotometry and microscopic imaging analysis. Results The optimum extraction process was that Schizonepeta tenuifolia was added with 8 times of water and extracted for 6 h; The inclusion process was as follows: the ratio of volatile oil to β -cyclodextrin was 1:8(mL:g), 8 times of water was added, and the mixture was grinded by a multifunctional colloid mill for 30 min. Conclusion: The selected process is reasonable and feasible, and can be used to extract volatile oil from Schizonepeta tenuifolia and prepare the inclusion of volatile oil with β-cyclodextrin. To optimize the preparation process of inclusion compound of forsythia suspense mint oil-β-cyclodextrin (β-CD) by Haoxing JM colloid mill. Methods Taking the yield and inclusion rate of inclusion compound as evaluation indexes, single factor experiment combined with Box-Behnken response surface method was used. The effects of the ratio of β-CD to water, the ratio of Fructus Forsythiae peppermint oil to β-CD and the inclusion time on the inclusion process were investigated. The formation of the inclusion compound of forsythia suspense mint oil -β-CD was preliminarily verified by TLC, infrared spectroscopy and microscopic images. Results The β-CD inclusion technology of forsythia suspense mint oil was better.
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